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Multiple relapses of visceral leishmaniasis in a patient with HIV in India: a treatment challenge

Shalom Patole1, Sakib Burza2, George M Varghese1

  • 1Department of Medicine and Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|June 15, 2014
PubMed

Visceral Leishmaniasis (VL) is an opportunistic infection amongst HIV-infected people in several endemic countries, and the clinical management of this co-infection poses several challenges. Here we describe a co-infected patient in India who failed to respond to miltefosine monotherapy and subsequently relapsed following two further (different) regimens of liposomal amphotericin B. He was then successfully treated with a combination of 30 mg/kg liposomal amphotericin B and 14 days of 100mg/day oral miltefosine.

Keywords:
HIV infectionRelapseTreatmentVisceral leishmaniasis

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