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Related Concept Videos

Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Healing II: Complications01:24

Healing II: Complications

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Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Trends and epidemiology of children treated in specialized burn centers in the Netherlands between 2009 and 2022.

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Related Experiment Video

Updated: Apr 28, 2026

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
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Reconstructive surgery after burns: a 10-year follow-up study.

M J Hop1, L C Langenberg2, J Hiddingh3

  • 1Association of Dutch Burn Centres, Maasstad Hospital, Rotterdam, The Netherlands; Department of Plastic, Reconstructive and Hand Surgery, MOVE Research Institute, VU University Medical Centre, Amsterdam, The Netherlands.

Burns : Journal of the International Society for Burn Injuries
|June 15, 2014
PubMed
Summary

Reconstructive surgery was performed in 13% of burn patients over 10 years, with scar contracture being the main reason. This study provides crucial data on burn reconstructive surgery needs.

Keywords:
BurnCostsEpidemiologyReconstructive surgery

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Area of Science:

  • Burn surgery
  • Plastic surgery
  • Trauma surgery

Background:

  • Limited understanding of reconstructive surgery prevalence post-burns.
  • Need for data on burn reconstructive surgery incidence, predictors, and costs.

Purpose of the Study:

  • Analyze the prevalence of reconstructive surgery after burns.
  • Identify predictors, indications, techniques, and medical costs associated with reconstructive surgery post-burns.

Main Methods:

  • Retrospective cohort study in Dutch burn centers (1998-2001).
  • Inclusion of acute burn patients with a 10-year follow-up.
  • Collection of patient, injury, and reconstructive surgery data.

Main Results:

  • 13.0% of burn patients (n=229/1768) underwent reconstructive surgery.
  • Average of 3.6 procedures per patient; hands and head/neck were most frequently reconstructed.
  • Scar contracture was the primary indication; release plus skin grafting/flaps was the common technique. Mean 10-year cost was €8342.

Conclusions:

  • Elucidated the reconstructive needs of burn patients.
  • Provides reference data for future studies on improving scar quality and reducing reconstructive surgery demand.