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Updated: Apr 28, 2026

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Targeting cytokine networks in KRAS-driven tumorigenesis

Hadrien G Golay1, David A Barbie

  • 1Department of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA.

Expert Review of Anticancer Therapy
|June 15, 2014
PubMed
Summary

KRAS mutations drive aggressive cancers and resist direct targeting. New therapies disrupting cytokine signaling networks offer a promising strategy to overcome treatment resistance in KRAS-driven tumors.

Keywords:
JAKKRASTBK1/IKKepsiloncytokinestargeted therapy

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