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Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor
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Three structurally similar odorants trigger distinct signaling pathways in a mouse olfactory neuron

Y Yu1, N P Boyer2, C Zhang1

  • 1Department of Biological and Chemical Sciences, Illinois Institute of Technology, 3101 S. Dearborn Street, Chicago, IL 60616, USA.

Neuroscience
|June 15, 2014
PubMed
Summary

Olfactory sensory neurons (OSNs) can activate distinct signaling pathways using a single olfactory receptor, revealing complex information processing in smell. This plasticity in G-protein-coupled receptor signaling offers insights beyond olfaction.

Keywords:
adenylate cyclasecalcium imagingolfactory neuronolfactory receptorphospholipase Csensory transduction

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