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Infectious causes of childhood disability: results from a pilot study in rural Bangladesh
Gulam Khandaker1, Mohammad Muhit2, Harunor Rashid3
1National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Sydney, NSW 2145, Australia The Discipline of Paediatrics and Child Health, The University of Sydney, Sydney, NSW 2145, Australia The Marie Bashir Institute for Emerging Infections and Biosecurity (MBI), Sydney Medical School, The University of Sydney, Sydney, NSW 2145, Australia gulam.khandaker@health.nsw.gov.au.
Insights
Infectious diseases significantly contribute to severe childhood disabilities in rural Bangladesh. Nearly 18% of disabilities studied were linked to infectious causes, highlighting a critical public health issue.
Area of Science:
- Global Health
- Pediatrics
- Infectious Diseases
Background:
- Childhood disability presents a significant global health challenge.
- Understanding the etiological factors of childhood disability is crucial for effective intervention.
- Infectious diseases are a suspected major contributor to childhood disability in low-resource settings.
Purpose of the Study:
- To determine the proportion of severe childhood disabilities in rural Bangladesh attributable to infectious causes.
- To identify specific infectious agents contributing to childhood disability.
Main Methods:
- A community-based survey utilizing the Key Informants Method was conducted.
- The study screened 1069 children for severe childhood disability.
- Data collection occurred between September 2011 and March 2012 in a rural Bangladeshi sub-district.
Main Results:
- Out of 1069 children screened, 859 had severe disabilities.
- The most prevalent conditions included cerebral palsy (37.7%), hearing impairment (23.4%), and physical impairment (17.1%).
- A total of 17.9% of disabilities were linked to infectious origins (7.1% confirmed, 10.8% probable).
Conclusions:
- Infectious diseases represent a substantial cause of severe childhood disability in rural Bangladesh.
- The findings underscore the importance of addressing infectious diseases to reduce childhood disability burden.
- Further research into specific infectious etiologies is warranted.
Purpose:
To identify the contribution of infectious aetiologies to major childhood disabilities in Bangladesh.
Methods:
Active community-based survey was conducted for severe childhood disability using the Key Informants Method between September 2011 and March 2012 in a rural sub-district of Bangladesh.
Results:
We screened 1069 children and identified 859 with severe disabilities. The mean age of the disabled children was 8.5 year and 42.9% were girls. The major forms of impairments/conditions were cerebral palsy (n = 324, 37.7%), hearing impairment (n = 201, 23.4%), physical impairment (n = 147, 17.1%), visual impairment (n = 49, 5.7%), cerebral palsy with epilepsy (n = 39, 4.5%) and epilepsy (n = 41, 4.7%). Congenital rubella syndrome was identified in 1.1% (n = 9). 7.1% disabilities resulted from clinically confirmed infections, and another 10.8% originated from probable infections; thus a total of 17.9% disabilities were related to an infectious origin.
Conclusions:
Infectious diseases appear to be one of the major causes of severe childhood disability in rural Bangladesh.
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