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Updated: Apr 28, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
Published on: May 1, 2018
Asymptotic solution of the diffusion equation in slender impermeable tubes of revolution. I. The leading-term
1Centre de Biophysique Moléculaire, CNRS-UPR4301, Rue C. Sadron, 45071 Orléans, France; Le STUDIUM (Loire Valley Institute for Advanced Studies), 3D av. de la Recherche Scientifique, 45071 Orléans, France; and Semenov Institute of Chemical Physics RAS, 4 Kosygina St., 117977 Moscow, Russia.
Abstract:
The anisotropic 3D equation describing the pointlike particles diffusion in slender impermeable tubes of revolution with cross section smoothly depending on the longitudinal coordinate is the object of our study. We use singular perturbations approach to find the rigorous asymptotic expression for the local particles concentration as an expansion in the ratio of the characteristic transversal and longitudinal diffusion relaxation times. The corresponding leading-term approximation is a generalization of well-known Fick-Jacobs approximation. This result allowed us to delineate the conditions on temporal and spatial scales under which the Fick-Jacobs approximation is valid. A striking analogy between solution of our problem and the method of inner-outer expansions for low Knudsen numbers gas kinetic theory is established. With the aid of this analogy we clarify the physical and mathematical meaning of the obtained results.
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