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Aneurysm associated with chronic mucocutaneous candidiasis during long-term therapy with ketoconazole
D Leroy1, A Dompmartin, J P Houtteville
1Service de Dermatologie, Centre Hospitalier Universitaire, Caen, France.
Dermatologica
|January 1, 1989
Abstract:
A little girl who was suffering from chronic mucocutaneous candidiasis also had a cellular immune deficiency and undetectable IgA levels. She was treated continuously for 6 years with ketoconazole at the same dosage of 200 mg/day. She was rapidly clear from infection and did not relapse although her immune abnormalities persisted. During this long-term therapy, voluminous fusiform intracranial aneurysm appeared, causing a paresis of the four limbs. Are they mycotic aneurysms?