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Management of neonatal proptosis: a systematic review
Benjamin P Erickson1, David T Tse1
1Bascom Palmer Eye Institute, Miami, Florida, United States.
Insights
Neonatal proptosis, or bulging eyes at birth, requires prompt diagnosis. This study reviews three challenging cases, highlighting key presentations and behaviors of common implicated lesions.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Neonatology
Background:
- Gross proptosis at birth is rare and can indicate serious underlying conditions.
- Neonatal presentations of diseases differ significantly from those in older children, impacting prognosis.
- A systematic approach is crucial for managing neonatal proptosis effectively.
Observation:
- Presents three challenging cases of neonatal proptosis.
- Details the clinical presentation and biological behavior of implicated lesions.
- Emphasizes the importance of a structured diagnostic framework.
Findings:
- Discusses common lesions causing neonatal proptosis.
- Highlights variations in presentation and prognosis between neonates and older children.
- Underscores the potential for vision compromise, disfigurement, and life-threatening outcomes.
Implications:
- Informs clinical decision-making for neonatal proptosis.
- Aids in early diagnosis and management of potentially life-threatening conditions.
- Contributes to understanding the unique aspects of neonatal ocular emergencies.
Abstract:
Gross proptosis presenting at birth is an uncommon manifestation of a variety of lesions that can compromise vision and result in disfigurement or even loss of life. Notably, many disease entities have different presentations and prognoses in neonates compared to older children. A structured mental framework is essential to an efficient and coordinated response. We present three challenging cases of neonatal proptosis and discuss the clinical presentation and biological behavior of the lesions that are most often implicated.
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