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Updated: Apr 28, 2026

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
[Pregnancy and substance use in France: a literature review]
A Dumas1, L Simmat-Durand1, C Lejeune2
1EHESS, CNRS UMR 8211, Inserm U 988, université Paris Descartes, Cermes 3, 45, rue des Saints-Pères, 75270 Paris cedex 06, France.
Objectives:
Substance use during pregnancy is an important public health issue. It requires identifying at-risk populations and risk perception among women.
Materials And Methods:
A literature review was conducted. It included French studies conducted since 2000 on substance use during pregnancy (tobacco, alcohol, marijuana, psychotropic drugs) and risk perception.
Results:
In France, in 2010, 24% of pregnant women smoke--17% in the 3rd trimester. Depending on studies, the prevalence of alcohol use ranged from 12 to 63% and binge drinking ranged from 1 to 7%; daily drinking was below 0.5%. Marijuana use ranged from 1 to 3%, and psychotropic drugs ranged from 2 to 4%. Little research has been dedicated to risk perception. Studies show a lack of awareness about the equivalence of risks between fermented and distilled beverages and about the risks of moderate smoking during pregnancy.
Conclusion:
Data is lacking to characterize at-risk populations and mechanisms underlying risky behaviors.
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