Panic disorder due to ingestion of single dose ecstasy

Ecstasy or MDMA (3,4 methylenedioxymethamphetamine) is a popularly consumed substance worldwide. There have been various reports documented in the literature that have attributed MDMA to precipitating the onset of a wide range of persistent psychiatric symptoms. Additionally, there is increasing evidence of a permanent injury to the serotonergic neurons. In this case report, a person demonstrating panic disorder after the ingestion of a single dose of MDMA is described and potential mechanisms of action are reviewed.