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Strong mixed-handedness in schizophrenia
Felipe Ortuño1, Pilar López, Ignacio Landecho
1Department of Psychiatry and Medical Psychology, University of Navarra Medical School, Pamplona, Spain.
Schizophrenia may be linked to mixed-handedness (MH), particularly in males. This study found a significant association between strong MH and schizophrenia, suggesting a potential neurological indicator.
Area of Science:
- Neuroscience
- Psychiatry
- Human Lateralization
Background:
- Schizophrenia's lateralization remains debated.
- Previous studies show mixed results regarding handedness in schizophrenia.
- Lack of specificity in differentiating left-handedness from mixed-handedness (MH) in prior research.
Purpose of the Study:
- To investigate the relationship between mixed-handedness (MH) and schizophrenia.
- To address the specificity issue in previous handedness studies on schizophrenia.
- To explore sex differences in the association between MH and schizophrenia.
Main Methods:
- Utilized Annett's hand preference questionnaire for accurate assessment.
- Differentiated between left-handedness and mixed-handedness (MH).
- Conducted sex-specific analysis on a small patient cohort.
Main Results:
- Observed a significant relationship between strong mixed-handedness (MH) and schizophrenia in male patients.
- Highlighted the importance of sex differentiation in handedness studies.
- Confirmed a shift away from dexterity in schizophrenic patients, with specific findings for MH.
Conclusions:
- Strong mixed-handedness (MH) is significantly associated with schizophrenia in males.
- Accurate assessment of handedness, including MH, is crucial for understanding schizophrenia.
- Sex-specific analyses are vital for uncovering nuanced relationships in neurological disorders.
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