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Updated: Apr 28, 2026

Corneal Donor Tissue Preparation for Endothelial Keratoplasty
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[The Boston keratoprosthesis].

Liqiang Wang1, Yifei Huang2, Chodosh James

  • 1Department of Ophthalmology, PLA Genreral Hospital, Beijing 100853, China.

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|June 17, 2014
PubMed
Summary

The Boston Keratoprosthesis (KPro), an artificial cornea, has seen design improvements and better complication management. These advances expand its use for severe corneal diseases, offering improved vision and retention rates.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Regenerative Medicine

Context:

  • Severe corneal diseases and graft failures necessitate advanced treatment options.
  • The Boston Keratoprosthesis (KPro) is an artificial cornea gaining widespread use globally.
  • Traditional penetrating keratoplasty has limitations for certain patient prognoses.

Purpose:

  • To summarize advancements in Boston type I KPro design.
  • To review strategies for managing post-operative complications.
  • To highlight the expanded indications and improved outcomes of KPro technology.

Summary:

  • Modifications to the Boston type I KPro design and post-operative care have enhanced its efficacy.
  • KPro is increasingly accepted as a primary surgical choice for patients with poor prognoses for traditional corneal transplants.
  • Outcomes regarding visual acuity, graft retention, and infection rates have significantly improved.

Impact:

  • KPro provides a viable alternative for visual rehabilitation in patients with severe corneal conditions.
  • The technology's improved outcomes and expanded indications offer hope for better patient prognoses.
  • Utilizing allograft corneas as carriers may address donor cornea shortages, particularly in regions like China.