Related Experiment Video

Updated: Apr 28, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

22.1K

Ischemic digital ulcers affect hand disability and pain in systemic sclerosis

Luc Mouthon1, Patrick H Carpentier1, Catherine Lok1

  • 1From the Université Paris Descartes, Faculté de Médecine, Service de Médecine interne, Centre de référence pour les vascularites nécrosantes et la sclérodermie systémique, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (APHP), Paris; Service de Médecine vasculaire, CHU de Grenoble, Grenoble; Service de Dermatologie, Hôpital Sud, CHU Amiens, Amiens; Orgamétrie, Roubaix; Actelion Pharmaceuticals France, Paris; Service de Médecine interne, Centre de référence pour la sclérodermie systémique, Hôpital Claude Huriez, Université Lille 2, Lille; Service de Médecine interne, Hôpital Bretonneau, Tours; Service de Médecine interne, Hôpital Saint Eloi, Montpellier; Service de Médecine interne, Hôpital Sud, Rennes; Service de Médecine Interne, Centre Hospitalier Universitaire Hôtel Dieu, Nantes; Service de Dermatologie, Hôpital Charles Nicolle, Centre Hospitalier Universitaire, Rouen; Service de Dermatologie, Hôpital Dupuytren, CHU Limoges; Hôpital Saint Jacques, Besançon; Service de Dermatologie, Université Aix-Marseille, UMR 911, INSERM CRO2 UMR 911, Centre de recherche en oncologie biologique et oncopharmacologie, Hôpital de la Timone, Assistance Publique Hôpitaux de Marseille, Marseille, France.L. Mouthon, MD, PhD, Deputy Chief of Internal Medicine Department, Université Paris Descartes, Faculté de Médecine, Service de Médecine interne, Centre de référence pour les vascularites nécrosantes et la sclérodermie systémique, Hôpital Cochin, APHP; P.H. Carpentier, MD, Chief of Vascular Medicine Department, Service de Médecine vasculaire, CHU de Grenoble; C. Lok, MD, Chief of Dermatology Department, Service de Dermatologie, Hôpital Sud, CHU Amiens; P. Clerson, MD, Director, Orgamétrie; V. Gressin, MD, Medical Director, Actelion Pharmaceuticals France; E. Hachulla, MD, PhD, Deputy Chief of Internal Medicine Department, Service de Médecine interne, Centre de référence pour la sclérodermie systémique, Hôpital Claude Huriez,

The Journal of Rheumatology
|June 17, 2014
PubMed
Abstract

Keywords:
BOSENTANDIGITAL ULCERSDISABILITYHANDSYSTEMIC SCLEROSIS

More Related Videos

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

33.4K
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

3.3K

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
760
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
1.6K
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
694
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
29
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
656
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
926