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Misdiagnosed gastrinoma: A case report
Qi-Kai Sun1, Wei Wang2, Hang-Cheng Zhou3
1Department of General Surgery, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui 230001, P.R. China.
Oncology Letters
|June 17, 2014
Summary
This case study highlights a rare pancreatic gastrinoma misdiagnosed as a solid pseudopapillary tumor. Early detection and accurate diagnosis are crucial for effective treatment of pancreatic neuroendocrine tumors.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Gastrinoma, often in the pancreaticoduodenal region, is frequently misdiagnosed due to similar symptoms to other pancreatic tumors.
- A rare case of asymptomatic pancreatic tail gastrinoma initially misdiagnosed as a solid pseudopapillary tumor of the pancreas (SPTP) is presented.
Purpose of the Study:
- To report a rare case of pancreatic gastrinoma misdiagnosis.
- To investigate factors contributing to misdiagnosis of pancreatic neuroendocrine tumors.
- To improve clinical awareness and diagnostic accuracy for pancreatic neuroendocrine carcinoma.
Main Methods:
- Case report of a female patient with a pancreatic tumor.
- Surgical resection of the pancreatic tumor with spleen preservation.
- Six-year follow-up including imaging and clinical assessment.
- Pathological examination and review of clinical factors.
Main Results:
- Initial misdiagnosis as SPTP after surgical resection.
- Development of liver lesions and peptic ulcer during follow-up.
- Confirmation of malignant pancreatic neuroendocrine carcinoma with liver metastases.
- Successful liver transplant and good patient condition post-transplant.
Conclusions:
- Pancreatic neuroendocrine tumors can present asymptomatically and be misdiagnosed.
- Clinical vigilance and comprehensive diagnostic approaches are essential.
- This case underscores the importance of considering rare diagnoses in pancreatic oncology.
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