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Updated: Apr 28, 2026

Author Spotlight: Implementing the Enhanced Recovery After Surgery Concept in Rehabilitation Following Anterior Cruciate Ligament Reconstruction
Published on: March 1, 2024
Long-term deficits in quadriceps strength and activation following anterior cruciate ligament reconstruction
Dana M Otzel1, John W Chow2, Mark D Tillman3
1Study Conducted at Biomechanics Laboratory, University of Florida, 151 Florida Gym, Gainesville, FL 32611, USA; Geriatric Research Education and Clinical Centers, Malcom Randall VA Medical Center, 1601 SW Archer Rd, Gainesville, FL 32608, USA.
Objective:
Even some time after a ruptured ACL has been reconstructed thigh musculature atrophy, voluntary activation, and knee-extensor strength deficits may be encountered. The purpose of this study was to evaluate bilateral knee-extension strength, voluntary activation of the quadriceps, and thigh circumference in males and females with ACL reconstruction (ACLR).
Design And Participants:
Within-subject and between-subject designs were used to evaluate 24 unilateral ACLR individuals and 23 controls.
Main Outcome Measures:
Isokinetic knee-extension strength was assessed in ACLR participants while central activation ratio (CAR) and thigh circumference measures were obtained from both groups.
Results:
Knee-extensor strength deficits (p < .039) and lower CAR of the quadriceps were found in the ACLR limb compared to the uninvolved limb (p = .047). Extensor strength was greater in males (p < .001), however, CAR was not different between sexes (p = .086). No difference in voluntary activation was revealed among the ACLR limb, uninvolved limb, and control limb when compared as independent groups (p = .460). The strength deficits found in the ACLR limb are partly attributable to lower voluntary activation compared to the uninvolved leg, given that no difference was found in thigh circumference between legs.
Conclusion:
Clinicians should consider the deficits in muscle function when returning patients to pre-injury activity levels.
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