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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

88
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
88
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.6K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

38
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
38

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Related Experiment Video

Updated: Apr 28, 2026

Murine Model of Allergen Induced Asthma
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Published on: May 14, 2012

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Asthma and toxocariasis.

Lingling Li1, Wei Gao1, Xiao Yang2

  • 1Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|June 18, 2014
PubMed
Summary
This summary is machine-generated.

This study found a significant link between asthma and Toxocara infection. Increased Toxocara species seropositivity was observed in asthma patients, suggesting a potential connection.

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Allergy and Immunology

Background:

  • Asthma is a prevalent chronic respiratory disease in children and adults.
  • A potential link between asthma and toxocariasis, a parasitic infection, has been proposed.

Purpose of the Study:

  • To systematically review and meta-analyze existing data to determine the association between asthma and Toxocara species seropositivity.
  • To quantify the strength of this association.

Main Methods:

  • A comprehensive literature search was conducted across PubMed, EMBASE, and Web of Science until October 2013.
  • Data extraction and quality assessment were performed independently by two authors.
  • A random-effects meta-analysis model was used to estimate the pooled odds ratio.

Main Results:

  • Ten studies comprising 1,530 participants (723 cases, 807 controls) were included.
  • A significantly higher prevalence of Toxocara canis infection was found in asthma patients compared to controls (OR 3.36, 95% CI 1.76-6.42).
  • This association remained consistent when analyzing pediatric and adult populations separately.

Conclusions:

  • The findings support a positive association between asthma and Toxocara species seropositivity.
  • Toxocariasis may be a contributing factor or marker in asthma development or exacerbation.