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A controlled study of lithium carbonate in the treatment of alcoholism
J R de la Fuente1, R M Morse, R G Niven
1Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905.
Mayo Clinic Proceedings
|February 1, 1989
Abstract:
A prospective double-blind placebo-controlled trial conducted during a 6-month period showed that lithium carbonate was no better than placebo in producing total abstinence in patients with alcoholism, regardless of whether they were depressed. A high dropout rate, the effect of compliance, and difficulties in measuring improvement in these patients impose some limitations in interpreting the results of this study.