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Updated: Apr 28, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Biological effects and equivalent doses in radiotherapy: A software solution
Cyril Voyant1, Daniel Julian2, Rudy Roustit3
1University of Corsica, CNRS UMR SPE 6134, Campus Grimaldi, 20250 Corte, France ; Hospital of Castelluccio, Radiotherapy Unit, BP 85, 20177 Ajaccio, France.
Background:
The limits of TDF (time, dose, and fractionation) and linear quadratic models have been known for a long time. Medical physicists and physicians are required to provide fast and reliable interpretations regarding delivered doses or any future prescriptions relating to treatment changes.
Aim:
We, therefore, propose a calculation interface under the GNU license to be used for equivalent doses, biological doses, and normal tumor complication probability (Lyman model).
Materials And Methods:
THE METHODOLOGY USED DRAWS FROM SEVERAL SOURCES: the linear-quadratic-linear model of Astrahan, the repopulation effects of Dale, and the prediction of multi-fractionated treatments of Thames.
Results And Conclusions:
The results are obtained from an algorithm that minimizes an ad-hoc cost function, and then compared to an equivalent dose computed using standard calculators in seven French radiotherapy centers.
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