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Multiple cutaneous and hepatic hemangiomas in infants
Kristi M Canty1, Kimberly A Horii1, Hassan Ahmad1
1From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
Southern Medical Journal
|June 18, 2014
Summary
Twenty-two percent of infants with multiple cutaneous infantile hemangiomas had asymptomatic hepatic hemangiomas. Specific cutaneous hemangioma types, like miliary, indicate higher risk for liver involvement.
Area of Science:
- Pediatric Dermatology
- Pediatric Gastroenterology
- Diagnostic Imaging
Background:
- Infantile hemangiomas are common benign vascular tumors in infants.
- Hepatic hemangiomas can occur in infants with cutaneous infantile hemangiomas.
- Screening for hepatic hemangiomas is crucial for appropriate management.
Purpose of the Study:
- To determine the prevalence of hepatic hemangiomas in infants with cutaneous infantile hemangiomas screened by abdominal ultrasound.
- To identify cutaneous infantile hemangioma characteristics associated with hepatic involvement.
- To assess clinical factors predicting hepatic hemangioma presence.
Main Methods:
- Retrospective study of 37 infants with cutaneous hemangiomas from 2000-2007.
- Abdominal ultrasound used to screen for hepatic hemangiomas.
- Infants categorized by cutaneous hemangioma morphology; clinical, sonographic, and laboratory data collected.
Main Results:
- Eight of 37 infants (22%) were diagnosed with hepatic hemangiomas.
- Miliary, numerous small, or large plus small cutaneous hemangiomas increased likelihood of hepatic hemangiomas.
- No clinical history, physical findings, or lab abnormalities predicted hepatic involvement.
Conclusions:
- Clinically asymptomatic hepatic hemangiomas are present in 22% of infants with multiple cutaneous infantile hemangiomas.
- Certain cutaneous hemangioma morphologies are associated with hepatic hemangiomas.
- Clinical factors do not reliably predict hepatic involvement in this cohort.
