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The billion cell construct: will three-dimensional printing get us there?

Jordan S Miller1

  • 1Department of Bioengineering, Rice University, Houston, Texas, United States of America.

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Summary
This summary is machine-generated.

Bioengineers explore how engineered tissue structure impacts function. Three-dimensional printing offers new ways to create tissues, but current technology has limitations in achieving desired biological functions.

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Area of Science:

  • Biotechnology
  • Tissue Engineering
  • Bioengineering

Background:

  • The relationship between biological structure and function is fundamental.
  • Bioengineers aim to create functional living tissues by controlling their architecture.
  • Experimental approximation of tissue architecture is challenging.

Purpose of the Study:

  • To investigate the relationship between engineered tissue form and emergent function.
  • To explore the potential and limitations of three-dimensional printing in tissue engineering.

Main Methods:

  • Utilizing three-dimensional printing technology to fabricate living tissue constructs.
  • Experimental approaches to assess tissue architecture and biological function.

Main Results:

  • Three-dimensional printing provides a novel method for creating complex tissue architectures.
  • Current three-dimensional printing technologies present limitations in achieving desired functional outcomes.

Conclusions:

  • Three-dimensional printing is a promising tool for tissue engineering.
  • Further technological advancements are needed to fully bridge the gap between engineered tissue form and desired function.