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Related Experiment Videos

Intra-abdominal sepsis after hepatic resection.

R F Pace1, J I Blenkharn, W J Edwards

  • 1Hammersmith Hospital, Royal Postgraduate Medical School, London, England.

Annals of Surgery
|March 1, 1989
PubMed
Summary

Post-hepatic resection, intra-abdominal sepsis affects 28.6% of patients. Percutaneous drainage is an effective treatment for these infections, offering successful management for hepatic resection complications.

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Area of Science:

  • Hepatobiliary Surgery
  • Surgical Infections
  • Abdominal Imaging

Background:

  • Hepatic resection is a major surgical procedure with potential complications.
  • Intra-abdominal sepsis is a significant concern following liver surgery.
  • Understanding risk factors and management strategies is crucial for patient outcomes.

Purpose of the Study:

  • To investigate the incidence and risk factors of postoperative intra-abdominal sepsis after hepatic resection.
  • To evaluate the effectiveness of different management strategies for intra-abdominal infections.
  • To identify common pathogens involved in post-hepatectomy sepsis.

Main Methods:

  • Retrospective review of 130 hepatic resections performed over an 8-year period.
  • Analysis of patient data for evidence of culture-positive intra-abdominal collections.

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  • Identification of independent variables associated with sepsis development.
  • Comparison of treatment outcomes between operative and percutaneous drainage methods.
  • Main Results:

    • 36 out of 126 eligible patients (28.6%) developed culture-positive intra-abdominal collections.
    • Diagnoses of trauma or cholangiocarcinoma and need for reoperation for hemorrhage were significant risk factors.
    • Mixed bacterial cultures were common (50%), with Streptococcus faecalis, Staphylococcus epidermidis, Staphylococcus aureus, and Escherichia coli as frequent isolates.
    • Percutaneous drainage has largely replaced operative drainage and proven effective.
    • Six patients with sterile fluid collections experienced symptom relief after drainage.

    Conclusions:

    • Intra-abdominal sepsis is a frequent complication after hepatic resection.
    • Risk factors include trauma, cholangiocarcinoma, and postoperative hemorrhage requiring reoperation.
    • Nonoperative percutaneous drainage is an effective and successful management strategy for most cases.