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Use of ketamine in a newborn with refractory status epilepticus: a case report
Anna Tarocco1, Elisa Ballardini2, Giampaolo Garani2
1Department of Medical Sciences, Pediatric Section, S. Anna University Hospital, Ferrara, Italy.
Background:
Brain malformations represent a major cause of refractory seizures. Standardized protocols to treat status epilepticus of newborn are not available in the literature.
Patient:
We present a case report of use of ketamine administered to a late preterm with Pierre Robin sequence, lissencephaly, polymicrogyria, and severe epilepsy.
Results:
The infusion of ketamine permitted resolution of status epilepticus, cardiorespiratory stabilization, and improved parental care for 15 days. No significant side effects were noted.
Conclusion:
In the literature there are few studies regarding the use of ketamine for refractory status epilepticus, and only in nine of these described the use of, ketamine in children (2 months-18 years). This is the first report to document the effective use of ketamine in the newborn with status epilepticus.
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