Treatment of hepatic cancer by hepatic arterial infusion chemotherapy
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Updated: Sep 10, 2026

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats
Published on: April 15, 2016
1Department of Surgery, Hanzomon Hospital, Tokyo, Japan.
Abstract:
A group of 213 patients with advanced primary hepatic carcinomas and 353 patients with metastatic liver cancers were treated by the prolonged intra-arterial infusion of mitomycin C and 5-fluorouracil through a surgically placed catheter over a period of time from 1966 to 1987. Regionalized chemotherapy by hepatic arterial infusion for hepatic cancer produced a greater degree and higher incidence of response than are obtainable through systemic administration. Intra-arterial infusion chemotherapy seems to offer an exciting new avenue of approach to the control of hepatic cancer.
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