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Updated: Apr 28, 2026
Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
Published on: February 3, 2023
A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating
Meng Gao1, Choon Kiat Sim, Chris Wai Tung Leung
1Institute of Materials Research and Engineering (A*STAR), 3 Research Link, Singapore 117602.
Abstract:
We report the design and synthesis of a specific mitochondrial fluorescent probe AIE-MitoGreen-1 with AIE characteristics to monitor the mitochondrial morphology changes and identify the differentiation process of living brown adipose cells. The probe AIE-MitoGreen-1 has significant advantages such as high cellpermeability, good mitochondrial retention, low background fluorescence, large Stokes shift, and low toxicity.
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