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The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
Published on: October 24, 2018
The anhedonias: Clinical and neurobiological aspects
1Complejo Hospitalario Xeral-Cies, Vigo, Spain.
Abstract:
During the last 30 years there has been renewed clinical interest in the state of 'lack of pleasure' (anhedonia) seen in conditions such as schizophrenia and depression. In spite of some important work, confusion still remains about the term, behaviours and explanatory concepts pertaining to anhedonia. This paper reviews the clinical and basic scientific studies that throw light on this interesting clinical phenomenon and then presents a new model of anhedonia which can be tested empirically and should facilitate research in this field.
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