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Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

44
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
44
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

30
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
30
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

18
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
18
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

16
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
16

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Ischemic stroke in Greyhounds: 21 cases (2007-2013).

Marc Kent1, Eric N Glass, Allison C Haley

  • 1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.

Journal of the American Veterinary Medical Association
|June 19, 2014
PubMed
Summary
This summary is machine-generated.

Greyhounds appear predisposed to ischemic stroke, with hypertension possibly contributing. Coagulation abnormalities were not found to be a factor in these canine stroke cases.

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Area of Science:

  • Veterinary Neurology
  • Canine Medicine

Background:

  • Ischemic stroke is a serious neurological condition in dogs.
  • Understanding breed-specific predispositions is crucial for diagnosis and management.

Purpose of the Study:

  • To determine the prevalence of ischemic stroke in Greyhounds.
  • To investigate potential contributing factors such as coagulation abnormalities and hypertension in affected Greyhounds.

Main Methods:

  • A multi-institutional retrospective study reviewed medical records and MRI images of 21 Greyhounds diagnosed with ischemic stroke.
  • Prevalence was calculated and compared to non-Greyhound breeds.
  • Coagulation and blood pressure were assessed in affected dogs.

Main Results:

  • The prevalence of ischemic stroke in Greyhounds was 0.66%.
  • Greyhounds were significantly more likely to present with ischemic stroke compared to other breeds.
  • Hypertension was identified in 6 of 14 tested Greyhounds; coagulation abnormalities were not found.

Conclusions:

  • Greyhounds exhibit a predisposition to ischemic stroke.
  • Hypertension may be a contributing factor, while coagulation issues appear unlikely.
  • Monitoring blood pressure and considering antihypertensive treatment in Greyhounds with stroke is recommended.