Coronary sinus lead extraction in CRT patients with CIED-related infection: risks, implications and outcomes

M Lisy1, E Schmid, G Kalender

  • 1Department of General, Visceral, Thoracic and Vascular Surgery, Frankfurt‑Höchst City Hospital, Frankfurt, Germany - lisy90@googlemail.com.

Insights

Coronary sinus (CS) lead extraction in cardiac resynchronization therapy (CRT) systems with infection is feasible and safe. Complete removal of infected cardiac implantable electronic device (CIED) systems is recommended for optimal patient outcomes.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Device Technology

Background:

  • Cardiac resynchronization therapy (CRT) systems are crucial for heart failure management.
  • Infections associated with CRT systems pose significant clinical challenges.
  • Coronary sinus (CS) lead extraction is a complex procedure, especially in infected patients.

Purpose of the Study:

  • To evaluate the risks, implications, and outcomes of CS lead extraction in patients with CRT system infections.
  • To assess the safety and efficacy of lead extraction in a cohort of infected patients.

Main Methods:

  • Retrospective analysis of 40 transvenous CS lead extraction procedures (2000-2011).
  • Inclusion of nine patients with CRT system infections (sepsis, lead/valve endocarditis, pocket infection).
  • Comparison of outcomes between infected and non-infected subgroups regarding lead dwell time, extraction methods, complications, and hospitalization.

Main Results:

  • Infected leads had significantly longer in situ duration (49.7 months vs. 19.2 months).
  • Extraction in infected patients required more aggressive techniques and longer radiation exposure.
  • All patients achieved procedural success; however, infected patients experienced more minor complications (44.4% vs. 3.2%) and longer hospitalization (21.4 days vs. 9.6 days).

Conclusions:

  • Complete removal of infected CIED systems is supported, even with limited pocket site infection.
  • An interdisciplinary approach ensures safe CS lead extraction in high-risk infected patients.
  • Excellent outcomes and low complication rates are achievable with appropriate standards.
Abstract

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