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Updated: Apr 28, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Synthetic glycosylated natural products have satisfactory activities
1College of Chemistry, Chongqing Normal University, Chongqing 401331, China. huangdoctor226@163.com.
Abstract:
Many natural products contain sugar residues, which are essential components for great medicinal importance. The sugar moieties can improve water-solubility of natural products and decrease their toxicity. At the same time, the glycosidic residues are crucial for the activities of natural products. Much effort has been expended over the past decades in developing novel and efficient methodologies to synthesize the glycosylated natural products. This review highlights recent developments in the synthesis of glycosylated natural products. The structure-activity relationships of some of these glycosylated natural products, together with the structure characteristics of their interaction with the biological targets, are also involved.
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