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Updated: Apr 28, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
Published on: September 5, 2014
Exploration of chemically cross-linked metal-organic frameworks
1Department of Chemistry and Biochemistry, University of California, San Diego , 9500 Gilman Dr. La Jolla, San Diego, California 92093-0358, United States.
Abstract:
A series of geometrically constrained, cross-linked benzene dicarboxylic acid (bdc) derivatives have been synthesized and incorporated into the canonical isoreticular metal-organic framework (IRMOF) lattice. Only certain cross-links, which allow for the proper relative orientation of the bdc subunits, form the desired IRMOF. Design criteria from these cross-linked ligands allowed for the rational design of two oligomeric ligands composed of three bdc monomers tethered together. These oligomeric ligands were also readily incorporated into an IRMOF lattice with a high degree of crystallinity and porosity, providing a new dimension to rational ligand design for metal-organic frameworks.
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