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A multifaceted pharmacist intervention to improve antihypertensive adherence: a cluster-randomized, controlled trial
K Stewart1, J George, K P Mc Namara
1Centre for Medicine Use and Safety, Monash University, Melbourne, Vic., Australia.
Journal of Clinical Pharmacy and Therapeutics
|June 20, 2014
Summary
A community pharmacist intervention improved adherence to antihypertensive medications and reduced systolic blood pressure (BP). This study highlights the role of pharmacists in managing hypertension and improving patient outcomes.
Area of Science:
- Pharmacology
- Public Health
- Clinical Pharmacy
Background:
- Antihypertensive medication non-adherence affects approximately 50% of patients within 12 months.
- Improved adherence to antihypertensives offers significant individual and population health benefits.
- Community pharmacists can play a key role in enhancing medication adherence and blood pressure control.
Purpose of the Study:
- To assess the effectiveness of a community pharmacist-led intervention aimed at improving adherence to antihypertensive medications.
- To evaluate the impact of the intervention on blood pressure (BP) control among hypertensive patients.
Main Methods:
- A prospective, non-blinded, cluster-randomized controlled trial.
- Inclusion of adult patients with primary hypertension who received antihypertensives in the prior six months.
- Intervention included a BP monitor, self-monitoring training, motivational interviewing, medication review, and refill reminders.
Main Results:
- The intervention group showed a significantly greater reduction in systolic blood pressure (10.0 mmHg vs. 4.6 mmHg).
- A higher proportion of non-adherent patients in the intervention group became adherent by six months (61.8% vs. 39.2%).
- Among patients with elevated baseline BP, the intervention group experienced a greater systolic BP reduction (7.2 mmHg).
Conclusions:
- Community pharmacist interventions can effectively improve adherence to antihypertensive medications.
- The intervention led to a significant reduction in systolic blood pressure.
- Pharmacist-led support is valuable for managing hypertension and improving patient adherence and BP control.
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