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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Diabetes Mellitus: Type 2 and Gestational01:22

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes Mellitus: Introduction01:26

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Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and...
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Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

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Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated...
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Diabetes: Management and Pharmacotherapy01:15

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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Consensus statement on diabetes in children.

K M Prasanna Kumar1, N Prabhu Dev2, K V Raman3

  • 1Consultant Endocrinologist, Bangalore Diabetes Hospital, Vasanthnagar, Bangalore, India.

Indian Journal of Endocrinology and Metabolism
|June 20, 2014
PubMed
Summary
This summary is machine-generated.

The incidence of Type 1 Diabetes Mellitus (T1DM) in children is alarmingly high, leading to severe health issues and societal challenges. Improved healthcare access and HCP training are crucial to prevent child mortality from T1DM.

Keywords:
Awareness creationType 1 Diabetesguidelines on insulin usepatient centric approachrole of policy makers and Government

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Area of Science:

  • Pediatrics
  • Endocrinology
  • Public Health

Background:

  • Type 1 Diabetes Mellitus (T1DM) incidence in children is rising significantly, posing a major pediatric health concern.
  • The disease's impact extends beyond affected children, affecting families and requiring societal awareness.
  • Barriers in healthcare access, awareness, and systemic issues hinder optimal T1DM management in India.

Purpose of the Study:

  • To address the growing challenge of T1DM in children.
  • To create a platform for stakeholders to discuss T1DM management issues.
  • To advocate for improved T1DM care and reduce child mortality.

Main Methods:

  • Convened the first international consensus meeting on diabetes in children.
  • Facilitated discussions on academic, administrative, and healthcare system challenges.
  • Focused on patient-centered management strategies.

Main Results:

  • Identified significant barriers to T1DM care, including lack of awareness and healthcare access.
  • Highlighted the need for improved training for healthcare professionals (HCPs).
  • Emphasized the critical gap in managing T1DM compared to Type 2 Diabetes Mellitus (T2DM).

Conclusions:

  • Urgent need for enhanced HCP training and systemic improvements in T1DM care.
  • Advocacy is essential to ensure "No child should die of diabetes".
  • Addressing societal apathy and improving healthcare delivery are paramount for better T1DM outcomes.