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Postpolypectomy Fever, a rare adverse event of polypectomy: nested case-control study
Seung-Hoon Lee1, Kyung-Jo Kim1, Dong-Hoon Yang1
1Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Clinical Endoscopy
|June 20, 2014
Summary
Postpolypectomy fever (PPF) is a rare complication after colonoscopy, occurring in 0.2% of patients. Hypertension and large polyps (>2 cm) are identified as key risk factors for developing PPF.
Area of Science:
- Gastroenterology
- Endoscopy
- Public Health
Background:
- Postpolypectomy fever (PPF) without complications like perforation or hemorrhage is uncommon.
- Limited data exists on the incidence and risk factors of PPF.
Purpose of the Study:
- To determine the incidence of PPF among inpatients undergoing colonoscopic polypectomy.
- To identify risk factors associated with PPF.
Main Methods:
- A case-control study involving 7 PPF patients matched with 70 controls from 3,444 patients.
- Univariate and multivariate analyses were used to identify risk factors and calculate adjusted odds ratios (ORs).
Main Results:
- The incidence of PPF was 0.2% (7 patients).
- Large polyps (>2 cm) and hypertension were significantly associated with increased PPF risk (adjusted ORs 1.08 and 14.40, respectively).
- PPF was linked to a prolonged hospital stay.
Conclusions:
- While PPF is rare, it can extend hospitalization duration.
- Hypertension and large polyp size are significant risk factors for PPF.
