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Hemi-depersonalization syndrome.

Yasser Khazaal1, Martin Preisig, Daniele Fabio Zullino

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|June 20, 2014
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Summary
This summary is machine-generated.

This case study details a patient with obsessive-compulsive disorder who experienced hemi-depersonalization. The condition, characterized by a detached feeling of the body

Keywords:
Depersonalizationdelusionsobsessive–compulsive disorderpsychosis

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Psychology

Background:

  • Depersonalization episodes can arise from various factors.
  • Obsessive-compulsive disorder (OCD) is a recognized mental health condition.
  • Hemi-depersonalization is a rare subtype of depersonalization.

Purpose of the Study:

  • To report a unique case of hemi-depersonalization syndrome in a patient with pre-existing OCD.
  • To investigate the relationship between hemi-depersonalization, delusions, and OCD.
  • To evaluate treatment response for hemi-depersonalization and associated symptoms.

Main Methods:

  • Case report of a single patient with OCD.
  • Clinical observation of symptoms including hemi-depersonalization and delusional ideation.
  • Pharmacological intervention with citalopram and olanzapine.
  • Assessment of symptom remission and persistence.

Main Results:

  • The patient presented with a sensation of left-sided bodily detachment (hemi-depersonalization) and an isolated delusion.
  • Symptoms were inconsistent with neurological distribution, affecting the entire left side of the body.
  • Citalopram was ineffective, but olanzapine rapidly remitted hemi-depersonalization and delusions.
  • Obsessive-compulsive symptoms persisted despite treatment for depersonalization.

Conclusions:

  • Hemi-depersonalization syndrome in this case appears independent of the co-occurring OCD.
  • The syndrome, along with delusions, is likely a manifestation of a psychotic reaction.
  • Olanzapine demonstrated efficacy in treating this specific psychotic presentation.