Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 28, 2026

Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration
06:42

Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration

Published on: May 24, 2024

2.1K

[Techniques to study transendothelial migration in vitro].

L Knopfová, P Bouchal, J Smarda

    Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti
    |June 20, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.

    Frontiers in cell and developmental biology·2023
    Same author

    Two types of high inductive electromagnetic stimulation and their different effects on endothelial cells.

    Physiological research·2019
    Same author

    Transcription factor c-Myb inhibits breast cancer lung metastasis by suppression of tumor cell seeding.

    Oncogene·2017
    Same author

    Osteogenic Potential of the Transcription Factor c-MYB.

    Calcified tissue international·2016
    Same author

    [Building Mass Spectrometry Spectral Libraries of Human Cancer Cell Lines].

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2016
    Same author

    Cyanobacterial ultrastructure in light of genomic sequence data.

    Photosynthesis research·2016
    Same journal

    68Ga-DOTATOC PET/CT - a case report of synchronous oncological duplicity with high expression of somatostatin receptors.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2026
    Same journal

    Differences in the imaging of Erdheim-Chester disease using FDG-PET/CT, NaF-PET/CT examinations, and skeletal scintigraphy. Regression of the disease after treatment with cladribine combined with cyclophosphamide and anakinra.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2026
    Same journal

    From progression to complete remission - a case study of successful pemigatinib treatment in a patient with metastatic FGFR2+ cholangiocarcinoma.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2026
    Same journal

    Second and subsequent lines of systemic therapy in endometrial cancer - a real-life clinical experience.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2026
    Same journal

    Chronic low-grade fever or fever with mild lymphadenopathy may indicate Castleman disease if no malignant, autoimmune, or infectious cause of the lymphadenopathy is identified.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2026
    Same journal

    Clinical presentations of the most common histiocytic disorders.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2026
    See all related articles

    Metastatic cancer spread is dangerous. This review classifies and analyzes in vitro methods for studying cancer cell transendothelial migration, aiding antimetastatic therapy development.

    Area of Science:

    • Oncology and Cell Biology
    • Investigating the cellular mechanisms of cancer metastasis.

    Context:

    • Cancer cell dissemination to secondary sites is a critical, life-threatening aspect of the disease.
    • Transendothelial migration, the process of crossing blood vessel walls, is a vital step in the metastatic cascade.
    • Understanding this process is key to developing targeted antimetastatic therapies.

    Purpose:

    • To review and classify various in vitro techniques used to study cancer cell transendothelial migration.
    • To analyze the advantages and disadvantages of different in vitro models.
    • To provide insights into selecting appropriate methods for oncological research.

    Summary:

    • The review categorizes and evaluates in vitro methods for studying cancer cell transendothelial migration.

    More Related Videos

    Study of Cell Migration in Microfabricated Channels
    09:36

    Study of Cell Migration in Microfabricated Channels

    Published on: February 21, 2014

    11.5K
    Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System
    10:25

    Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System

    Published on: September 20, 2019

    6.5K

    Related Experiment Videos

    Last Updated: Apr 28, 2026

    Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration
    06:42

    Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration

    Published on: May 24, 2024

    2.1K
    Study of Cell Migration in Microfabricated Channels
    09:36

    Study of Cell Migration in Microfabricated Channels

    Published on: February 21, 2014

    11.5K
    Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System
    10:25

    Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System

    Published on: September 20, 2019

    6.5K
  • It discusses the feasibility, accuracy, and relevance of these techniques compared to in vivo models.
  • The analysis highlights the variability and challenges associated with current in vitro approaches.

    • Impact:

    • Facilitates informed selection of in vitro models for studying cancer metastasis.
    • May guide the development of improved experimental systems for transendothelial migration research.
    • Contributes to the advancement of targeted antimetastatic therapeutic strategies.