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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antimicrobial stewardship: another focus for patient safety?
Pranita D Tamma1, Alison Holmes, Elizabeth Dodds Ashley
1aDivision of Pediatric Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA bFaculty of Medicine, National Centre for Infection Prevention and Management, Imperial College, London, UK cAssociate Director of Clinical Pharmacy Services, University of Rochester Medical Center, Rochester, New York, USA.
Antimicrobial stewardship is crucial for preserving antibiotic effectiveness against rising resistance. Framing stewardship as a patient safety initiative can improve understanding and adoption by the public and administrators.
Area of Science:
- Infectious Diseases
- Public Health
- Healthcare Management
Background:
- Antibiotic resistance is a growing global threat, necessitating strategies beyond new drug development.
- Preserving the efficacy of existing antibiotics is essential.
- Antimicrobial stewardship programs (ASPs) are key to antibiotic preservation but often lack broad understanding.
Purpose of the Study:
- To explore the intersection of antimicrobial stewardship and patient safety initiatives.
- To advocate for integrating antimicrobial stewardship under the broader umbrella of patient safety.
- To demonstrate how ASPs can achieve established patient safety goals.
Main Methods:
- Review of existing literature on antimicrobial stewardship and patient safety.
- Analysis of overlapping principles and practices.
- Identification of concrete examples linking stewardship activities to patient safety outcomes.
Main Results:
- Antimicrobial stewardship directly contributes to patient safety by optimizing antibiotic use and combating resistance.
- Framing stewardship within patient safety enhances its recognition and acceptance among stakeholders.
- ASPs can be effectively aligned with recognized patient safety objectives.
Conclusions:
- Patient safety is an intrinsic element of effective antimicrobial stewardship.
- Emphasizing the link between antimicrobial stewardship and patient safety is vital for its wider acceptance and implementation.
- Integrating stewardship into patient safety frameworks can improve public and administrative understanding and support.
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