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Updated: Apr 27, 2026

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
Published on: July 4, 2017
Accuracy of MR in growth plate measurement
Juan Manuel Shiguetomi-Medina1, Ole Rahbek, Steffen Ringgaard
1Orthopaedic Research Laboratory, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark, jmshigue@gmail.com.
Purpose:
To analyze the accuracy of growth-plate thickness measurements detected on 1.5-T and 7-T MR images using histology sections as a standard of reference.
Materials And Methods:
Four defrosted pig tibiae were 1.5-T MR scanned and one fresh tibia was 7-T MR scanned. The height of the growth plate was measured and compared to histology.
Results:
Histology measurements showed a mean growth plate thickness of 467 μm (SD = 82.2). The mean growth plate thickness measured in the 7-T MR images was 465 μm (SD = 62.2) and 1,325 μm (SD = 183.5) on 1.5-T MR measurements. We found a better correspondence between the growth plate thickness measured on the 7-T MR and histology samples compared to 1.5 T.
Conclusions:
The growth plate can be identified and measured with high accuracy using 7-T MR. 1.5-T MR can only describe some morphological characteristics.

