Cyclodextrins in capillary electrophoresis: recent developments and new trends

Area of Science:

• Analytical Chemistry
• Separation Science

Background:

• Capillary electrophoresis (CE) is a widely researched separation technique.
• Previous reviews have covered CE broadly but lacked specific focus on cyclodextrins (CDs).

Purpose of the Study:

• To provide a focused review on cyclodextrins in capillary electrophoresis (CD-CE) for the period of January 2013 to February 2014.
• To summarize recent contributions, analyze publication trends, and predict future research interests in CD-CE.

Main Methods:

• Systematic review of research articles and reviews published between January 2013 and February 2014.
• Categorization of publications by application: solute-CD binding constant estimation, chiral analysis, and achiral analysis.
• Statistical analysis of publication trends and future predictions.

Main Results:

• The review covers 19% practical uses (solute-CD binding constant estimation), 38% chiral analysis, and 24% achiral analysis applications.
• Nine comprehensive tables summarize recent contributions.
• Statistical analysis highlights current and expected research interests in CD-CE.

Conclusions:

• Cyclodextrins play a significant role in advancing capillary electrophoresis techniques.
• Future research in CD-CE is expected to focus on practical applications and chiral separations.
• The review outlines trends and initiatives addressing real-world needs in CD-CE.