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Metabolic syndrome as a risk factor for elevated intraocular pressure
Nedime Sahinoglu-Keskek1, Sakir Ozgur Keskek2, Selim Cevher3
1Nedime Sahinoglu-Keskek, MD, Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.
Pakistan Journal of Medical Sciences
|June 21, 2014
Summary
Metabolic syndrome is linked to higher intraocular pressure, but not central corneal thickness. This study highlights a key relationship between metabolic syndrome and eye pressure, important for understanding ocular health.
Area of Science:
- Ophthalmology
- Endocrinology
- Metabolic Diseases
Background:
- Metabolic syndrome is a cluster of conditions increasing risk for heart disease, stroke, and diabetes.
- Intraocular pressure (IOP) is a key factor in glaucoma pathogenesis.
- Central corneal thickness (CCT) can influence IOP measurements.
Purpose of the Study:
- To investigate the association between metabolic syndrome and intraocular pressure (IOP).
- To compare central corneal thickness (CCT) between subjects with and without metabolic syndrome.
- To explore the relationship between metabolic syndrome components and IOP.
Main Methods:
- Cross-sectional study with 162 participants (89 metabolic syndrome, 73 control).
- Ophthalmological examinations including IOP and CCT measurements.
- Biochemical analysis (glucose, lipids) and anthropometric measurements (waist circumference, blood pressure).
Main Results:
- Significantly higher IOP in the metabolic syndrome group compared to controls (p = 0.008).
- No significant difference in CCT between the groups (p = 0.553).
- Most metabolic syndrome components were associated with elevated IOP (p < 0.05).
Conclusions:
- A positive relationship exists between metabolic syndrome and intraocular pressure.
- No association found between metabolic syndrome and central corneal thickness.
- This study is the first to report a positive relationship between metabolic syndrome and IOP while comparing CCT.
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