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Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast
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A microfluidic system for studying ageing and dynamic single-cell responses in budding yeast.

Matthew M Crane1, Ivan B N Clark1, Elco Bakker1

  • 1SynthSys - Center for Synthetic and Systems Biology and School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

Plos One
|June 21, 2014
PubMed
Summary

We developed ALCATRAS, a microfluidic system for long-term, high-density single-cell measurements. This technology enables detailed studies of cellular variability and responses in controlled, dynamic environments.

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