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Related Concept Videos

The Placebo Effect01:54

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The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
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Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

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Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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The placebo effect in asthma.

Stefanie Dutile1, Ted J Kaptchuk, Michael E Wechsler

  • 1Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Current Allergy and Asthma Reports
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PubMed
Summary
This summary is machine-generated.

The placebo effect, a complex phenomenon, is well-studied in asthma due to objective outcomes. Research on placebo response in asthma offers insights into its mechanisms and current treatment strategies.

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Area of Science:

  • Psychoneuroimmunology
  • Respiratory Medicine
  • Clinical Pharmacology

Background:

  • The placebo effect is a well-documented phenomenon across various clinical conditions.
  • Research often focuses on subjective outcomes in conditions like depression, chronic pain, and irritable bowel syndrome (IBS).
  • Asthma presents a unique model for placebo research due to its measurable, objective outcomes.

Purpose of the Study:

  • To review the current literature on placebo effects in general.
  • To specifically examine the placebo response within the context of asthma.
  • To explore the mechanisms, patient populations, influenced outcomes, and augmentation potential of placebo effects in asthma.

Main Methods:

  • Comprehensive literature review of placebo research.
  • Focus on studies investigating placebo response in asthma.
  • Analysis of mechanisms, patient-specific responses, and outcome measures.

Main Results:

  • Asthma serves as a valuable model for understanding placebo mechanisms due to objective outcome measures.
  • Placebo response studies in asthma illuminate current diagnostic and treatment paradigms.
  • The review synthesizes knowledge on who responds to placebos, which outcomes are affected, and how the effect can be enhanced.

Conclusions:

  • Placebo research in asthma provides critical insights into the mind-body connection in disease.
  • Understanding placebo mechanisms in asthma can refine therapeutic strategies and diagnostic approaches.
  • Further investigation into augmenting placebo effects may offer novel treatment avenues for respiratory conditions.