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Structural network efficiency is associated with cognitive impairment in small-vessel disease

Andrew J Lawrence1, Ai Wern Chung2, Robin G Morris2

  • 1From the Stroke & Dementia Research Centre (A.J.L., A.W.C., T.R.B.), St George's University of London; Department of Psychology (R.G.M.), Institute of Psychiatry, King's College London; and Clinical Neurosciences (H.S.M.), University of Cambridge, UK. alawrenc@sgul.ac.uk.

Neurology
|June 22, 2014
PubMed
Summary

Cerebral small-vessel disease (SVD) disrupts brain network connectivity, impacting cognitive function. Network efficiency measures are stronger predictors of cognitive decline than conventional MRI markers in SVD patients.

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