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Langerhans cell histiocytosis presenting as isolated mediastinal mass in an infant
Mohammed Ramzan1, Satya Prakash Yadav
1Pediatric Hematology Oncology and BMT Unit, Department of Pediatrics, Fortis Memorial Research Institute, Gurgaon, Haryana, India. Correspondence to: Dr Satya P Yadav, Department of Pediatrics, Fortis Memorial Research Institute, Gurgaon, Haryana, India. satya_1026@hotmail.com.
Background:
Isolated mediastinal involvement in Langerhans cell histiocytosis (LCH) has been rarely reported.
Case Characteristics:
A 3-month-old boy presented with history of low grade intermittent fever, cough and noisy breathing for 2 weeks.
Observation:
A chest X-ray showed massive mediastinal widening. Biopsy of the mass confirmed LCH.
Outcome:
Patient is doing well after one year of treatment with LCH III protocol.
Message:
Langerhans cell histiocytosis should be considered in differential diagnosis of mediastinal mass in infants.
