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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
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Atrial septal defect coexistent with Sjögren's syndrome
Farook Ahmad1, Muhammad Athar Sadiq1, Kok Han Chee1
1Department of Medicine, University Malaya Medical Centre, 50603, Kuala Lumpur, Malaysia.
Summary
This case highlights a potential link between atrial septal defect and Sjögren's syndrome. Closing the defect improved heart failure symptoms in a patient with pulmonary hypertension and dry eyes/mouth.
Area of Science:
- Cardiology
- Rheumatology
- Ophthalmology
Background:
- Pulmonary hypertension often co-occurs with atrial septal defects and connective tissue diseases.
- Sjögren's syndrome is an autoimmune disorder affecting exocrine glands.
Observation:
- A 74-year-old woman presented with heart failure, dry eyes, and salivary gland issues.
- Echocardiogram revealed an atrial septal defect with severe pulmonary hypertension.
- Diagnosis confirmed Sjögren's syndrome with positive autoantibodies (Anti-nuclear factor, Anti-Ro/SS-A).
Findings:
- Transcatheter closure of the atrial septal defect led to significant clinical improvement.
- The patient's symptoms of heart failure resolved post-procedure.
- This case suggests a possible association between atrial septal defect and primary Sjögren's syndrome.
Implications:
- This case underscores the importance of investigating cardiac causes in patients with Sjögren's syndrome.
- Early diagnosis and intervention, such as transcatheter closure, can improve outcomes.
- Further research is warranted to explore the potential link between these conditions.
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