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Aspiration pneumonitis caused by polyethylene glycol-electrolyte solution treated with conservative management
Ricardo A Mosquera1, Mark McDonald1, Cheryl Samuels1
1High Risk Children Comprehensive Care Clinic, University of Texas Health Science of Houston, 6410 Fannin Street, Suite 500, Houston, TX 77030, USA.
Insights
Accidental polyethylene glycol (PEG) solution aspiration caused lung inflammation in a child. Conservative management, without invasive procedures like bronchoalveolar lavage, proved effective for PEG pneumonitis.
Area of Science:
- Pediatric Pulmonology
- Gastroenterology
- Toxicology
Background:
- Polyethylene glycol (PEG) electrolyte solution is an osmotic laxative used for bowel preparation.
- Accidental intratracheal instillation of PEG can lead to pneumonitis.
- Nasogastric tube (NGT) migration is a potential risk factor for accidental tracheal instillation.
Purpose of the Study:
- To report a case of PEG-induced pneumonitis in a pediatric patient.
- To evaluate the efficacy of conservative management for PEG pneumonitis.
- To discuss the management of PEG aspiration in the pediatric population.
Main Methods:
- Case report of a 9-year-old boy with accidental PEG solution aspiration.
- Clinical observation including monitoring of oxygenation and respiratory rate.
- Non-invasive management approach without bronchoalveolar lavage (BAL) or intubation.
Main Results:
- The patient developed hypoxemia and tachypnea after PEG aspiration.
- Successful treatment was achieved with close monitoring and conservative care.
- No invasive interventions such as BAL or intubation were required.
Conclusions:
- PEG pneumonitis can be managed effectively with conservative measures in select pediatric patients.
- Invasive interventions like BAL may not always be necessary for PEG aspiration.
- Clinical judgment is crucial in determining the appropriate management strategy for PEG pneumonitis.
Abstract:
Polyethylene glycol (PEG) electrolyte solution, Golytely, is an osmotic laxative commonly used in preoperative bowel cleansing. In this case report, a 9-year-old boy developed aspiration pneumonitis following accidental infusion of PEG solution into his right lung following migration of his nasogastric tube (NGT). Hypoxemia and tachypnea without respiratory failure were observed after infusion. Because PEG is a nonabsorbable toxic material, previous case reports have advocated for the performance of bronchoalveolar lavage (BAL) in the treatment of PEG pneumonitis. With close monitoring, our patient was able to be successfully treated without the need for invasive interventions including BAL or intubation. Generalizations about PEG absorption in the lung based on its permeability in the gastrointestinal tract should not deter the use of more conservative treatment in the appropriate patient.
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