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Surgical Correction for Pediatric Epiblepharon and Trichiasis
Published on: July 8, 2025
[Pylephlebitis in pediatric patients]
Lucas Alberto Degano1, Soraya Anis El Kik1, Ana Rizzi1
1Hospital Prof. Dr. Juan P. Garrahan, Buenos Aires.
Insights
Pylephlebitis, a rare but serious condition linked to appendicitis, requires prompt treatment including antibiotics and anticoagulation. Early diagnosis and intervention are crucial for improving outcomes and reducing mortality in affected children.
Area of Science:
- Medical Science
- Pediatric Gastroenterology
- Infectious Diseases
Background:
- Pylephlebitis, defined as thrombophlebitis of the portal vein, is a rare condition with high morbidity and mortality.
- It is frequently associated with acute appendicitis and can lead to long-term complications like portal vein cavernoma and portal hypertension.
Abstract:
Pylephlebitis is defined as thrombophlebitis of the portal vein or its tributaries. It is a rare disease commonly associated with acute appendicitis and it has a high rate of morbidity and mortality. Doppler ultrasound and computed tomography scan are the methods of choice to confirm diagnosis. The most frequent long-term complication in these patients is portal vein cavernoma, with subsequent portal hypertension. An early diagnosis, timely antibiotic therapy and removal of infection are essential therapeutic measures to diminish mortality. The need for anticoagulation therapy in children remains controversial. We report on a child with acute abdomen and sepsis with a diagnosis of pylephlebitis secondary to appendiceal inflammation. The patient received long-term antibiotic therapy and subcutaneous anticoagulation. Deferred appendectomy was performed with favorably outcome.
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Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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