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The Right Subclavian Artery Arising as the First Branch of a Left-Sided Aortic Arch

Lazaro E Hernandez1, Charles W Shepard2, Simon D Bamforth3

  • 1Department of Pediatrics, University of Minnesota, Amplatz Children's Hospital, Minneapolis, MN, USA herna426@umn.edu.

World Journal for Pediatric & Congenital Heart Surgery
|June 25, 2014
PubMed

Insights

This study details a rare left-sided aortic arch branching pattern where the right subclavian artery arises first, followed by a common trunk for carotid arteries. This finding is relevant to congenital heart disease and genetic conditions.

Area of Science:

  • Cardiovascular Anatomy
  • Developmental Biology
  • Clinical Genetics

Background:

  • Atypical aortic arch branching patterns can be associated with congenital heart defects.
  • Understanding these variations is crucial for accurate diagnosis and surgical planning.
  • Genetic factors, such as chromosomal deletions, can influence cardiovascular development.

Observation:

  • A rare left-sided aortic arch variant was identified.
  • The first branch was the right subclavian artery.
  • Common carotid arteries originated from a shared trunk following the right subclavian artery.

Findings:

  • The described aortic arch branching pattern is highly unusual.
  • The patient presented with transposition of the great arteries (TGA) and an 18q23 deletion.
  • This anatomical finding provides insights into complex cardiac morphogenesis.

Implications:

  • Echocardiographers should consider this branching pattern when evaluating aortic arch abnormalities.
  • The findings contribute to the understanding of embryological development of the aortic arch and its branches.
  • Correlating vascular anomalies with genetic syndromes like 18q23 deletion aids in predicting associated cardiac conditions.

Keywords:
18q23 deletiondouble aortic archesembryonic development

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