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Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses
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Delayed fatherhood.

Gerald Lawson1, Richard Fletcher2

  • 1Former Consultant Obstetrician and Gynaecologist, John Hunter Hospital, Newcastle, New South Wales, Australia.

The Journal of Family Planning and Reproductive Health Care
|June 25, 2014
PubMed
Summary
This summary is machine-generated.

Older fatherhood is linked to increased risks for stillbirths and later-life conditions like autism. Advanced paternal age may also affect pregnancy outcomes, necessitating further research into these health implications.

Keywords:
ageing spermdelayed paternityhealth issues for the childpaternal age effectpregnancy complications

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Area of Science:

  • Reproductive Health
  • Pediatric Health
  • Genetics

Background:

  • Global birth data shows a consistent rise in average paternal age.
  • Increasing paternal age raises concerns about potential adverse pregnancy and child health outcomes.
  • Age-related changes in sperm quality may pose risks to offspring conception and development.

Purpose of the Study:

  • To identify pregnancy complications associated with advanced paternal age.
  • To investigate fetal anomalies and child health issues linked to older fathers.
  • To review evidence of sperm and genetic material impairment in older men.

Main Methods:

  • Literature search conducted to gather relevant studies.
  • Reviewed evidence on pregnancy complications.
  • Examined data on fetal anomalies and child health outcomes.

Main Results:

  • Increased risk of stillbirths observed with older fathers.
  • Slightly elevated risks for autism, bipolar disorder, and schizophrenia in offspring.
  • Recognized increased risk of achondroplasia and higher rates of Caesarean sections for mothers.

Conclusions:

  • Advanced paternal age is associated with specific adverse pregnancy and child health outcomes.
  • Evidence suggests potential impairment in sperm quality and genetic material with paternal aging.
  • Further comprehensive longitudinal studies are required to fully elucidate these risks.