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Published on: August 24, 2019
The minimum clinically important improvement in the incremental shuttle walk test following cardiac rehabilitation
Linzy Houchen-Wolloff1, Sally Boyce2, Sally Singh2
1Centre for Exercise and Rehabilitation Science (CERS), Respiratory Biomedical Research Unit (BRU), University Hospitals of Leicester NHS Trust, UK Linzy.Houchen@uhl-tr.nhs.uk.
Background:
The aim was to establish the minimum clinically important difference (MCID) in the incremental shuttle walk test (ISWT) following cardiac rehabilitation.
Design:
This was a service evaluation, utilising anchor- and distribution-based methods.
Methods:
Two hundred and twenty patients performed an ISWT following a six-week cardiac rehabilitation programme comprising supervised aerobic exercise, secondary prevention education and a home exercise programme.
Primary Outcome:
Patient perception of change in ISWT distance following cardiac rehabilitation. After completing cardiac rehabilitation, subjects were asked to identify, from a five-point Likert scale, their perceived change in exercise performance (range: from 'better' to 'worse'). Two distribution-based methods were also employed (standard deviation (SD) and effect size). The agreement between all measures was observed.
Results:
Mean (SD) age was 65.0 (10.5) years, body mass index 28.4 (5.1), 170 male. The baseline ISWT was 390.8 (173.1) metres (m), which increased to 456.0 (186.7) m (mean change 65.2 (95% confidence interval 55.4-74.9) m after cardiac rehabilitation (p < 0.001)). In those rating their exercise tolerance as 'slightly better', the mean improvement was 70.0 (95% confidence interval 51.5-88.5) m. The SD method yielded a minimum clinically important difference value of 36.65 m and the effect size for the change was 0.38. The agreement between the patients' perception of change and distribution-based methods was poor.
Conclusions:
The minimum clinically important difference for the ISWT following cardiac rehabilitation is 70 m. This patient-reported value is a more sensitive measure and has poor agreement with distribution-based estimates. This value may help clinicians interpret ISWT change in patients, help researchers estimate sample size and aid comparison between studies, when the ISWT is the primary outcome.

