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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Value of pharmacist medication interviews on optimizing the electronic medication reconciliation process.
Audrey Lee1, Arjun Varma2, Maureen Boro3
1Professor of Pharmacy Practice and Regional Coordinator, University of the Pacific (UOP), Thomas J. Long (TJL) School of Pharmacy and Health Sciences; Clinical Associate Professor, University of California at San Francisco (UCSF), School of Pharmacy; and Clinical Pharmacist, Internal Medicine , San Francisco VA Medical Center (SFVAMC) .
Combining pharmacist interviews with electronic medical record review (EMRR) significantly improves medication history accuracy, identifies more discrepancies, and prevents medication errors in hospitalized patients.
Area of Science:
- Pharmacology
- Patient Safety
- Health Informatics
Background:
- Accurate medication histories are crucial for patient safety.
- Current methods like electronic medical record review (EMRR) may have limitations in capturing complete medication information.
- The impact of different medication history acquisition methods on medication safety requires further investigation.
Purpose of the Study:
- To compare the accuracy and clinical impact of pharmacist-obtained medication histories using EMRR alone versus a combination of direct patient interviews and EMRR.
- To evaluate the number of discrepancies, recommendations, and medication errors associated with each method.
Main Methods:
- An 18-week prospective study involving patients admitted to an Inpatient Medicine Service.
- Pharmacist-conducted medication reconciliation using EMRR within 48 hours of admission.
- Data collection through chart review to compare EMRR alone versus EMRR combined with patient interview.
Main Results:
- The combined interview and EMRR group identified significantly more discrepancies (986) than EMRR alone (513).
- More recommendations were generated in the combined group (260 vs. 97).
- Fewer medication errors were found with EMRR alone (55) compared to the combined group (134), with omitted medications being the most common error type.
Conclusions:
- Pharmacist-led medication interviews integrated with EMRR enhance the identification of potentially harmful medication discrepancies.
- This combined approach shows promise in preventing medication errors during hospital admissions.
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