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Cell Population Analyses During Skin Carcinogenesis

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Published on: August 21, 2013

Non-hereditary cherubism.

Babita Niranjan¹, Nd Shashikiran¹, Shilpy Singla¹

¹Department of Pedodontics and Preventive Dentistry, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.

Journal of Oral and Maxillofacial Pathology : JOMFP

|June 25, 2014

Summary

Cherubism is a rare genetic disorder causing jaw swelling in children. This case report details a 13-year-old girl with progressive cherubism symptoms.

Keywords:

Fibro-osseous disorders multinucleated giant cells osteoclastic lesion

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Area of Science:

Genetics
Pediatrics
Oral and Maxillofacial Surgery

Background:

Cherubism is an autosomal dominant, non-neoplastic, fibro-osseous jaw disorder.
Typically affects children aged 2-5 years, predominantly males, presenting with bilateral cheek swelling.
Characterized by jaw enlargement, leading to a distinct 'cherubic' facial appearance.

Observation:

This report focuses on a 13-year-old female patient.
The patient presented with progressive swelling of the cheeks.
Radiographic findings typically show multilocular, bilateral radiolucent jaw lesions.

Findings:

The case highlights cherubism occurring in an older female child.
Demonstrates the characteristic clinical presentation of progressive facial swelling.
Confirms radiographic features consistent with cherubism.

Implications:

Emphasizes the importance of recognizing cherubism beyond its typical demographic.
Suggests continued observation for self-limiting fibro-osseous conditions.
Contributes to understanding the variable presentation of genetic jaw disorders.